ISSN 2285-5750, ISSN CD-ROM 2285-5769, ISSN-L 2285-5750, ISSN Online: 2393 – 2260
 

The management of 45 Ca uptake in skeletal, cardiac and smooth muscle tissue in rats of different ages. the impact of acute and long term treatment with D3vitamin

Published in Scientific Papers. Series D. Animal Science, Vol. LV
Written by Flory Revnic, Bogdan Paltineanu, Cosmin Sonea, Cristian Romeo Revnic, Cătălina Pena

The aim of the present study was to investigate the effect of acute and long term treatment with D3 vitamin upon 40 Wistar rats aged between 6-24 months old. Significant modification in 45Ca uptake in striated muscle from young rats with acute and long term treatment with D3 -vitamin has been noticed. Acute and long term treatment with D3 -vitamin in old rats determined an increase in 45Ca at the level of heart and aorta. The results have an important clinical significance in administration of D3 -vitamin in aging people because of the Ca accumulation danger on cardiac muscle and aorta leading to acceleration of functional disorders of the cardiovascular system affected by atherosclerosis process.

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