Published in Scientific Papers. Series D. Animal Science, Vol. LXVII, Issue 2
Written by Angelica DOCAN, Lorena DEDIU, Mirela CREȚU, Iulia GRECU, Alina MACOVEIU (DOBRE), Ion VASILEAN
Fructose is a highly lipogenic sugar and excessive fructose intake stimulates endogenous glucose production and lipid synthesis in the liver. Therefore, the present study aims to investigate the amelioration of liver impairment induced by high fructose dietary doses following dietary supplementation with krill oil. 45 exemplars of Carassius auratus calico weighing 150 grams, were randomly distributed into three experimental diets including V1 - Control, fish fed with a normal diet, V2 - fish fed with 1% fructose, V3 - fish fed with 2% fructose, respectively, at the end of 90 days: V1 - Control, fish fed with a normal diet, V2 - fish fed with 1% krill oil, V3 - fish fed with 2% krill oil. The blood tissues were collected to analyze hematological parameters (red blood cell counts (RBCc, x 106/µl), the hematocrit (PCV, %), hemoglobin concentrations (Hb, gl/dl,) HEM, VEM, CHEM and serum biochemistry parameters (GLU, TRIG, ALT and AST). In addition, the organosomatic indices (HIS, VSI) and proximate composition (water, lipid, ash, and protein content) were analyzed. No differences between the control and treated fish from the two experimental diets were observed in hematological parameters. After 90 days fructose-treated fish showed increased AST and ALT levels. Our results showed that daily krill oil supplementation in the Carassius auratus calico prevented fructose-induced hypertriglyceridemia.
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