Published in Scientific Papers. Series D. Animal Science, Vol. LXVIII, Issue 2
Written by Daniela ALBISORU, Nicoleta RADU, Oksana MULESA, Mihaela BEGEA, Viviana ROMAN
Red yeast rice is currently used in Asia as a dye for meat, fish, and other food products, as well as a food supplement due to its statin content. Reports worldwide have documented adverse effects, particularly in individuals with pre-existing health conditions. In this context, we conducted in vitro tests to assess the cytotoxicity of three red dyes derived from different types of red yeast rice. In our study, a normal human standardized cell line was exposed to these red dyes for 24 and 48 hours. The results obtained during these studies revealed that the red polyketides derived from Monascus ruber and Monascus purpureus display cytotoxicity for the studied cell line after 24 hours of exposure, cytotoxicity that persists after 48 hours of exposure only for Monascus purpureus. Red polyketides obtained from high-productivity Monascus sp do not exhibit cytotoxicity in vitro for the studied cell line.
[Read full article] [Citation]
